In addition to their affinity for D2 dopaminergic receptors, antipsychotic drugs prescribed for the treatment of psychotic disorders frequently exhibit anticholinergic side effects. Central M1, M4, or dual M1/M4 receptor agonists are among the current class of mAChR agonists that target psychosis....
Dementia is a progressive neurological disorder, which is often linked to negative connotations and stigmatising views perpetuated by its portrayal in media. Media frequently frames dementia as a catastrophic and inevitable decline, emphasising the loss of cognitive function of the individuals and their personhood. ...
With the aging of populations across the world combined with advances leading to extended lifespan, the incidence of frailty is on the rise. In the United States there are just over 60 million individuals over 65 years old at this time. ...
When actor Gene Hackman died on or around February 18, 2025, he was 95 years old. The medical examiner, Dr. Heather Jarrell, stated that hypertensive and atherosclerotic cardiovascular disease was the cause of his death, but also that "Alzheimer's disease was a significant contributing factor [1]." ...
The integration of Artificial Intelligence (AI)-driven personal assistants, such as Amazon's Alexa, into geriatric care presents a transformative approach to supporting aging populations. These technologies offer a range of benefits, including enhancing accessibility, promoting independence, mitigating social isolation, and assisting with cognitive engagement and mental health. ...
Isoniazid, a hydrazide of is nicotinic acid is one of the primary drugs used in Tuberculosis, which is highly bactericidal agent against the dividing tubercle bacilli. Most common adverse effects of this agent are Hepatitis, peripheral neuropathy and psychosis being rare one. Isoniazid-induced psychosis, though is rare, has been reported in patients. ...
The person-centered care approach has been demonstrated to have benefits for individuals with dementia residing in residential care facilities and the professionals who care for them. However, its implementation remains challenging, particularly because it necessitates a substantial shift in care culture. ...